For a patient on lithium, which of the following should be monitored to prevent toxicity?

Monitoring thyroid function is essential for patients on lithium therapy due to the medication’s potential effects on thyroid hormone levels. Lithium can interfere with the synthesis and release of thyroid hormones, potentially leading to hypothyroidism. Symptoms of hypothyroidism may include fatigue, weight gain, and depression, which can exacerbate the psychiatric condition being treated.

Regular assessment of thyroid function helps ensure early detection and management of any thyroid-related issues, reducing the risk of complications and optimizing the overall treatment plan. In contrast, while liver enzymes, blood glucose levels, and cholesterol levels can be relevant in other contexts, they are not the primary parameters directly affected by lithium and are therefore not routinely monitored for lithium toxicity prevention.