Which antidepressant should be avoided in patients with bulimia nervosa due to the risk of seizures?

The correct choice is bupropion, which is avoided in patients with bulimia nervosa due to its association with an increased risk of seizures, especially in individuals who may be engaging in purging behaviors. These behaviors, which can lead to electrolyte imbalances, significantly heighten the risk of seizures when bupropion is utilized.

In the context of treating bulimia nervosa, it is essential to understand the specific pharmacological profiles of various antidepressants and their potential side effects. Other options, such as fluoxetine, paroxetine, and citalopram, do not carry the same seizure risk, making them safer alternatives in managing depression or anxiety symptoms in this population. Fluoxetine, in particular, is often favored as it has been shown to help with bulimia nervosa and is generally considered safe regarding seizure activity. By understanding these distinctions, healthcare professionals can make informed decisions about treatment options for their patients.