Which complication of alcohol use disorder presents with a triad of ophthalmoplegia, ataxia, and confusion?

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Wernicke's encephalopathy is characterized by a classic triad of symptoms: ophthalmoplegia (eye muscle paralysis), ataxia (loss of full control of bodily movements), and confusion (cognitive dysfunction). This condition arises from thiamine (vitamin B1) deficiency, commonly seen in individuals with alcohol use disorder due to poor nutritional intake and absorption. The importance of recognizing these symptoms is critical because Wernicke's encephalopathy can progress to Korsakoff syndrome if untreated, leading to more severe cognitive impairments.

In this context, while Korsakoff syndrome does relate to alcohol use and cognitive dysfunction, it primarily presents with memory issues and confabulation rather than the acute symptoms of ophthalmoplegia and ataxia. Delirium tremens is another serious condition resulting from alcohol withdrawal, characterized by severe agitation, confusion, and hallucinations but does not include the specific triad mentioned. Cirrhosis primarily refers to liver damage rather than neurological symptoms. Thus, Wernicke’s encephalopathy is the correct condition associated with the specified triad of symptoms in those suffering from alcohol use disorder.

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