Which of the following is NOT an example of an SSRI?

Prepare for the Psychiatry Core Exam. Enhance your knowledge with flashcards and multiple choice questions, each offering hints and explanations for a better understanding. Ace your test with confidence!

Amitriptyline is not an example of a selective serotonin reuptake inhibitor (SSRI) because it belongs to a different class of antidepressants known as tricyclic antidepressants (TCAs). While SSRIs specifically target the reuptake of serotonin in the brain to help alleviate symptoms of depression and anxiety, TCAs like amitriptyline affect multiple neurotransmitter systems, including serotonin and norepinephrine, but are not selective in their mechanism of action.

Fluoxetine, sertraline, and citalopram are all commonly prescribed SSRIs, as they selectively inhibit the reuptake of serotonin at the synaptic cleft, enhancing serotonin's availability for receptor binding. This mechanism helps improve mood and alleviate symptoms of depression, making these medications effective for treating various psychiatric disorders.

Understanding the categories and mechanisms of different antidepressants is crucial in psychiatry, as it informs treatment decisions and potential side effects for patients.

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